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VIAGRA shouldn't be used with REVATIO or with other PAH treatment plans made up of sildenafil or some other PDE5 inhibitors (which include Adcirca® [tadalafil])
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Sildenafil was damaging in in vitro bacterial and Chinese hamster ovary cell assays to detect mutagenicity, and in vitro human lymphocytes and in vivo mouse micronucleus assays to detect clastogenicity.
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